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Duchefa chemicals for tissue culture lab activities

5-Fluorouracil (5-FU) - Duchefa

SKU
BIO-F0123
CAS number 51-21-8
Molecular weight C4H3FN2O2 = 130.1
Assay > 98 %
Loss on drying < 0.5 %
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Product description

5-Fluorouracil, a pyrimydine analogue, is an antineoplastic agent that acts as an antimetabolite to uracil. After intra-cellular conversion to the active deoxynucleotide, it interferes with the synthesis of DNA by blocking the conver-sion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase.

Storage condition

  • Store at 2-8 °C
  • Soluble in water (10 g/l)
  • Loss on drying < 0.5%

    • Hazard statements

  • H301 Toxic if swallowed
  • H312 Harmful in contact with skin
  • H332 Harmful if inhaled
  • H350 May cause cancer
  • H360 May damage fertility or the unborn child

    • Precautionary statements

  • P201 Obtain special instructions before use
  • P281 Use personal protective equipment as required
  • P301 IF SWALLOWED:
  • P308 IF exposed or concerned:
  • P310 Immediately call a POISON CENTER or doctor/physician
  • P313 Get medical advice/attention