Rifampicin - Duchefa

Rifampicin is active against gram-positive bacteria but less active against gram-negative bac-teria. It interferes with the synthesis of nucleic acids by inhibiting DNA dependent RNA polymerase. Resistance to rifampicin can develop rapidly. The degree of resistance varies depending on the site of mutation in the RNA polymerase.

Storage condition

Store dry at 2-8 °C

Soluble in dilute acid solution

Hazard statements

H302 Harmful if swallowed

H315 Causes skin irritation

H319 Causes serious eye irritation

H335 May cause respiratory irritation

H361 Suspected of damaging fertility or the unborn child

H362 May cause harm to breast-fed children

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood

P261 Avoid breathing dust/fume/gas/mist/vapours/spray

P263 Avoid contact during pregnancy/while nursing

P280 Wear protective gloves/protective clothing/eye protection/face protection

P305 IF IN EYES:

P308 IF exposed or concerned:

P313 Get medical advice/attention

P351 Rinse continuously with water for several minutes